Researchers tested CFS patients, chronic Lyme patients, and healthy controls. They looked at spinal fluid from all three populations and found over 700 unique proteins in the spinal fluid of CFS patients that were not evident in either of the other two groups. They also found close to 700 different proteins in the spinal fluid of the Lyme patients, again unique only to that group.
This study suggests several significant conclusions:
- Chronic Lyme is a unique condition, different than CFS (the symptoms are similar, so the two have been mistaken for each other in the past).
- CFS does have unique biomarkers that could help to diagnosis it more easily and accurately in the future.
- The identification of these proteins could eventually lead to blood-test biomarkers that could serve as diagnostic tools (it isn't practical or safe to use spinal fluid testing - you can't just go around spinal tapping everyone with chronic fatigue).